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pentobarbital will lower the level or influence of fosphenytoin by affecting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Observe.pentobarbital decreases levels of panobinostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Potent CYP3A4 inducers can lower panobinostat degrees by ~70% and bring about treatment method